Anti-ARC; clone 6F9.1

Code: MABC140 D2-231

Analysis Note

ControlHuman hippocampus tissue lysate

Application

Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, t...


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€396.00 EACH
€487.08 inc. VAT

Analysis Note

ControlHuman hippocampus tissue lysate

Application

Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, that targets ARC & has been tested in western blotting & IHC (Paraffin).

Research CategoryApoptosis & Cancer

Research Sub CategoryApoptosis - Additional

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ARC in human brain tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Activity-regulated cytoskeleton-associated protein (ARC), also known as Activity-regulated gene 3.1 protein homolog (ARG3.1), plays an important role in synaptic plasticity and the formation of long-term memory. ARC is enriched in the postsynaptic density of dendritic spines and regulates endocytosis of AMPA receptors in response to synaptic activity and is required for homeostatic synaptic scaling of AMPA receptors. ARC also plays a role in the regulation of cell morphology, cytoskeletal organization, stress fiber dynamics, and cell migration.

Immunogen

GST-tagged recombinant protein corresponding to human ARC.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Protein G Purified

Format: Purified

Quality

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected ARC in 200 µg of human hippocampus tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~ 45 kDa observed

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
clone6F9.1, monoclonal
Gene Informationhuman ... ARC(23237)
isotypeIgG1κ
NCBI accession no.NP_056008
Quality Level100
shipped inwet ice
species reactivityhuman
technique(s)western blot: suitable, immunohistochemistry: suitable (paraffin)
UniProt accession no.Q7LC44
This product has met the following criteria to qualify for the following awards:



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